BD-2, Human, Standard TMB ELISA Development Kit

Katalog-Nummer NB-50-1446-1000

Size : 1000Tests

Marke : Neo Biotech

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Telefonnummer : +1 850 650 7790

Product Specifications

Analytical sensitivity

Lot-specific

Assay range

Lot-specific

Hands-on time

1 hr 45 min

Time-to-result

24 hr 30 min

Homogenous (no wash)

No

Instrument

Colorimetric Microplate Reader

Product size

10 x 96 Tests

Contents

This Human beta-2 Defensin ELISA Kit includes Capture Antibody, Detection Antibody, Protein Standard, and HRP-conjugate. The HRP-conjugate is packaged separately.

Storage

Refer to product documentation for component specific storage temperature.

Protein name

beta-2 Defensin

Protein family

Growth Factors & Receptors

Species (tested)

Human

Assay kit format

ELISA Development Kit

Detector antibody conjugate

Biotin

Label or dye

HRP

About This Kit

900-T172K consists of: 900-T172 (capture antibody, detection antibody, and protein standard), and HRP-17UL (streptavidin HRP-conjugate).

Human beta-2 Defensin TMB ELISA Development Kit contains the key components required for the quantitative measurement of natural and/or recombinanthuman beta-2 Defensin in a sandwich ELISA format. Human beta-2 Defensin TMB ELISA Development Kit contains enough material to assay the target cytokine in at least 1,000 ELISA plate wells.

The TMB ELISA Buffer Kit (Product # 900-T00), sold separately, is recommended to be used in conjunction with this TMB ELISA Development Kit for optimal performance. This buffer kit contains all the necessary components to assay ten 96-well ELISA plates (included) and contains detailed handling instructions.

Target information

Defensins (alpha and beta) are cationic peptides with a broad spectrum of antimicrobial activity that comprise an important arm of the innate immune system. The alpha-defensins are distinguished from the beta-defensins by the pairing of their three disulfide bonds. To date, six human beta-defensins have been identified; BD-1, BD-2, BD-3, BD-4, BD-5 and BD-6. beta-defensins are expressed on some leukocytes and at epithelial surfaces. In addition to their direct antimicrobial activities, they can act as chemoattractants towards immature dendritic cells and memory T cells. The beta-defensin proteins are expressed as the C-terminal portion of precursors, and are released by proteolytic cleavage of a signal sequence and, in some cases, a propeptide sequence. Beta-defensins contain a six-cysteine motif that forms three intra-molecular disulfide bonds.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.