Baricitinib-d5 [1564241-79-7]
Katalog-Nummer HY-15315S-1mg
Size : 1mg
Marke : MedChemExpress
Baricitinib-d5 is the deuterium labeled Baricitinib. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
Baricitinib-d5 Chemische Struktur
CAS. Nr. : 1564241-79-7
This product is a controlled substance and not for sale in your territory.
Alle JAK Isoform-spezifische Produkte anzeigen:
Beschreibung |
Baricitinib-d5 is the deuterium labeled Baricitinib. Baricitinib (LY3009104; INCB028050) is a selective and orally bioavailable JAK1 and JAK2 inhibitor with IC50s of 5.9 nM and 5.7 nM, respectively. |
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In Vitro |
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. |
Molekulargewicht |
376.45 |
Formel |
C16H12D5N7O2S |
CAS. Nr. |
1564241-79-7 |
Unlabeled CAS |
1187594-09-7 |
SMILES |
N#CCC1(N2N=CC(C3=C4C(NC=C4)=NC=N3)=C2)CN(S(=O)(C([2H])([2H])C([2H])([2H])[2H])=O)C1 |
Versand | Room temperature in continental US; may vary elsewhere. |
Speicherung |
Please store the product under the recommended conditions in the Certificate of Analysis. |
Reinheit & Dokumentation | |
Verweise |
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Baricitinib-d5 Related Classifications
- Inflammation/Immunology
- Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
- JAK
Molaritätsrechner
Verdünnungsrechner
Die Formel zur Berechnung von Molaritäten
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
The dilution calculator equation
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Diese Gleichung wird häufig abgekürzt als: C1V1 = C2V2
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Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.
Keywords:
Baricitinib-d51564241-79-7LY3009104-d5INCB028050-d5JAKJanus kinaseInhibitorinhibitorinhibit