B Raf (BRAF) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5A9]
Katalog-Nummer TA500431BM
Size : 100ul
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B Raf (BRAF) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI5A9]
SKU
TA500431BM
BRAF mouse monoclonal antibody, clone 5A9, HRP conjugated
- TrueMAB™
Antibodies made against full-length proteins as antigens.
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| Product Data | |
| Clone Name | OTI5A9 |
|---|---|
| Application | FC, IF, IHC, IP, WB |
| Application | WB 1:1000~2000, IF 1:100, FLOW 1:100 |
| Reactivity | Human, Monkey, Mouse, Rat |
| Antibody Host | Mouse |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Immunogen | Full length human recombinant protein of human BRAF (NP_004324) produced in HEK293T cell. |
| Buffer | PBS (pH 7.3) containing 1% BSA, 50% glycerol. |
| Concentration | 0.5 mg/ml |
| Purification | Purified from mouse ascites fluids or tissue culture supernatant by affinity chromatography (protein A/G) |
| Conjugation | HRP |
| Storage | Store at -20°C as received. |
| Stability | Stable for 12 months from date of receipt. |
| Predicted Protein Size | 84.4 kDa |
| Gene Name | B-Raf proto-oncogene, serine/threonine kinase |
| Database Link | |
| Background | This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases.This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation,and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma,non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. |
| Synonyms | B-raf; B-RAF1; BRAF1; NS7; RAFB1 |
| Reference Data | |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Acute myeloid leukemia, Bladder cancer, Chemokine signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Focal adhesion, Glioma, Insulin signaling pathway, Long-term depression, Long-term potentiation, MAPK signaling pathway, Melanoma, mTOR signaling pathway, Natural killer cell mediated cytotoxicity, Neurotrophin signaling pathway, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Regulation of actin cytoskeleton, Renal cell carcinoma, Thyroid cancer, Vascular smooth muscle contraction |
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| SKU | Description | Size | ||
|---|---|---|---|---|
| CF500431 | Carrier-free (BSA/glycerol-free) BRAF mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) | 100 ug | | |
| TA500431 | BRAF mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) | 100 ul | | |
| TA500431AM | BRAF mouse monoclonal antibody, clone 5A9, Biotinylated | 100 ul | | |
| TA500431S | BRAF mouse monoclonal antibody, clone OTI5A9 (formerly 5A9) | 30 ul | | |
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