ATG4B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommended Dilution	WB: 1:1000
Reactivities	Human (Predicted: Mouse, Zebrafish, Bovine, Chicken)
Host	Rabbit
Isotype	Ig
Clonality	Polyclonal
Immunogen	This ATG4B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-290 amino acids from the Central region of human ATG4B.
Formulation	PBS with 0.09% (W/V) sodium azide
Concentration	lot specific
Purification	This antibody is purified through a protein A column, followed by peptide affinity purification.
Conjugation	Unconjugated
Storage	Store at -20°C as received.
Stability	Stable for 12 months from date of receipt.
Gene Name	autophagy related 4B cysteine peptidase
Database Link	NP_847896 Entrez Gene 66615 MouseEntrez Gene 23192 Human UniProt ID Q9Y4P1
Background	Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes.
Synonyms	APG4B; AUTL1
Reference Data
Protein Families	Protease
Protein Pathways	Regulation of autophagy