General Info
Host: | Rabbit |
Applications: | WB/IHC/IF/ELISA |
Reactivity: | Human/Rat/Mouse |
Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: | Rabbit polyclonal antibody anti-Endothelin receptor type B (31-80 aa) is suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence and ELISA research applications. |
Clonality: | Polyclonal |
Conjugation: | Unconjugated |
Isotype: | IgG |
Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
Concentration: | 1 mg/mL |
Dilution Range: | IHC-P 100-300WB 1:500-2000ELISA 1:10000-20000IF 1:50-200 |
Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Information
Gene Symbol: | EDNRB |
Gene ID: | 1910 |
Uniprot ID: | EDNRB_HUMAN |
Immunogen Region: | 31-80 aa |
Specificity: | ETBR Polyclonal Antibody detects endogenous levels of ETBR |
Immunogen: | Synthesized peptide derived from ETBR at the amino acid range 31-80 |
Description
Post Translational Modifications | Palmitoylation of Cys-402 was confirmed by the palmitoylation of Cys-402 in a deletion mutant lacking both Cys-403 and Cys-405. |
Function | Non-specific receptor for endothelin 1, 2, and 3. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. |
Protein Name | Endothelin Receptor Type BEt-BEt-BrEndothelin Receptor Non-Selective Type |
Database Links | Reactome: R-HSA-375276Reactome: R-HSA-416476 |
Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinInternalized After Activation By Endothelins |
Alternative Antibody Names | Anti-Endothelin Receptor Type B antibodyAnti-Et-B antibodyAnti-Et-Br antibodyAnti-Endothelin Receptor Non-Selective Type antibodyAnti-EDNRB antibodyAnti-ETRB antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance